Mentor and scientific compass
Dr Arkadi Prokopov
Physician in integrative medicine · hypoxia research and mitochondrial medicine
For more than four decades, Arkadi Prokopov has followed a single question: how does the body respond to controlled changes in oxygen supply — and what can we learn from it?
At a glance
1949
born in Moscow
1974–1980
medical degree
1994
based in Germany
40+
years of hypoxia research

His career started with research for people in extreme conditions: divers, mountaineers, cosmonauts. Not wellness — resilience in situations where oxygen runs short.
That work produced the principle known today as intermittent hypoxic–hyperoxic training: short phases of reduced and increased oxygen, carefully dosed and monitored throughout.
For ZELLGIPFEL he is the scientific reference point. He shaped the method we follow — sober, measurable and free of grand promises.
Background
Career
1949
Moscow
Born and raised in Moscow.
1974–1980
Medical studies
Medical degree with an early focus on breathing, circulation and adaptation to low oxygen.
1980–1993
Research for extreme conditions
Adaptation programmes for divers, high-altitude climbers and cosmonauts — the groundwork for today's interval protocols.
1994
Move to Heidelberg
Living and working in Germany since 1994, bringing hypoxia research into integrative medicine.
2000–2004
Consulting in the USA
From 2000 to 2004 he worked as a consultant in the United States, including on the engineering side of training equipment.
2005 –
Teaching, patents, practice
Several patents and papers on hypoxic–hyperoxic application, lectures and hands-on guidance — today mostly in Mallorca and Germany.
What drives him
Areas of focus
Three themes run through all of his work.
Intermittent hypoxia and hyperoxia
How much stimulus does the body need, how much recovery in between — and how do you steer both instead of improvising?
Mitochondria
The cell's power plants as the starting point: how cells handle oxygen, and how those processes can actually be measured.
Technology and safety
Device development, measurement and protocols that make every session monitorable and repeatable.
In his own words
Videos from his channel
Talks and contributions by Arkadi Prokopov — play them right here and switch to the next one with a single click.
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Talk in Mallorca
Talk · German · Video 1 of 5
Published work
Patents and publications
The complete record of his granted patents and published work.
Patents
Four granted patents covering ergometry and breathing technology.
- SU1984
Patent number: SU 1189425A
Ergometer for underwater biomedical research
Inventors: A. Prokopov
- DE1999
Patent number: DE 19912337
Tragbares Atemgerät für Training unter Sauerstoffmangel-Bedingungen
Portable Breathing Device for Hypoxic Training
Inventors: A. Prokopov, K. Buecken
- RU2016
Patent number: RU 2650205
Device for Production of Hypoxic, Hyperoxic and Normoxic Respiratory Mixtures and Interval Complex Normobaric Training
Inventors: A. Prokopov, D. Kolesov, I. Klementev, L. Fefilatev, A. Sedojkin, A. Brovko
- RU2023
Patent number: RU 2806613
Breathing Trainer
Inventors: A. Prokopov
Publications
Journal papers, book chapters and conference talks in chronological order.
- 2004Book chapter
1.Benefits of Modified Breathing Air for Spacecraft and Planetary Habitats
Prokopov A., Kotliar I.
In: On to Mars — Colonizing a New World. Eds. Zubrin R. M., Crossman F. Apogee Books, 2004. ISBN 1896522904
- 2007Journal paper
2.Exploring overlooked natural mitochondria-rejuvenative intervention: the puzzle of bowhead whales and naked mole rats
Prokopov A.
Rejuvenation Research, 2007, Vol. 10, No. 4, pp. 543–559
- 2007Journal paper
3.Intermittent Hypoxic Therapy / Training (IHT): the aetiologic and pathogenetic anti-aging treatment
Prokopov A., Voronina T.
Rejuvenation Research, 2007, Vol. 10, S1, p. 45
- 2007Conference talk
4.Clinical experience in a novel anti-aging treatment modality: the Intermittent Hypoxic Therapy (IHT)
Prokopov A., Voronina T.
Anti-Aging Conference London, The Royal Society of Medicine, 14–16 September 2007
- 2008Journal paper
5.Zelluläre Kraftwerke natürlich reparieren
Prokopov A.
CoMed, November 2008, pp. 37–38
- 2009Book chapter
6.Engineered natural longevity-enhancing interventions
Prokopov A., Voronina T.
In: Handbook on Longevity — Genetics, Diet and Disease. Eds. Bentely J. V., Keller M. A. Nova Science Publishers, Hauppauge NY, 2009. ISBN 978-1-60741-075-1
These are bibliographic references. Titles name research topics and are not a statement about any effect.
Please note
This page introduces a person and their professional work. It is not medical advice and makes no claims about treating illness.
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